Skin Whitening and Lightening – Glutathione Is The Master Antioxidant

Skin whitening and lightening is achievable since glutathione is also known as gamma-glutamylcysteinylglycine or GSH is an antioxidant formed from the amino acid cysteine, glutamate, and glycine. Virtually all your cells have glutathione, but this antioxidant is most highly concentrated in your liver, pancreas, spleen, and eyes. It is the body’s most renowned and powerful antioxidant that helps protect your body from free-radical damage, boosts the immune system and detoxifies the body1.


By helping your body detoxify, glutathione helps reduce your risk of developing cancer. Glutathione is able to fight cancer by causing malignant cells to die but keeping healthy cells alive. Glutathione also helps synthesize and repair DNA.  It also recycles vitamins which also act against free radicals2Further benefits of glutathione are its anti-aging effects that are highly remarkable from age spots of the skin and wrinkles, and it is also safe to use as a skin whitening treatment.


Your glutathione levels dwindle as you age. There are many causes of glutathione levels decreasing in the body, including environmental toxins, poor diet, stress, aging, infections, chemotherapy, and pollution. When glutathione becomes depleted it can no longer protect against free radicals, infections, or cancer and we can’t get rid of toxins. This leads to further sickness and soon we are in the downward spiral of chronic illness. Thus, taking glutathione supplements may offset the reduced glutathione levels caused by these factors.  


Glutathione: How does it effectively work in skin whitening?

When it comes to skin whitening, glutathione may have anti-melanogenic effects by converting melanin to a lighter color and deactivating the enzyme tyrosinase which helps produce the pigment. It also appears to work by ridding the body of toxins and free radicals that lead to age spots, sun spots, wrinkles, melasma or post inflammatory hyperpigmentation. It can help with cystic acne, acne-prone skin, red spots, and skin roughness while improving the overall texture, tone, elasticity, and smoothness of the skin. On top of this, Glutathione speeds up cell turnover, replacing the damaged cells – that give a dark appearance to the skin – with new cells 3.

Glutathione works faster than any other cosmetic product and is the best whitening treatment that lightens the skin without any component of harmful chemicals and ingredients. The whitening process of glutathione goes head to foot giving you a white, even skin tone in your whole body, and can go permanent if maintained. The lightening process starts in the dermis working its way out to the epidermis, thus giving a glow to your skin without worrying for irritations and burns from chemicals because it does not contain other harmful ingredients that can compromise your general well being.

Aside from skin whitening effect, it is also an antioxidant that helps strengthen immune function that is why glutathione is greatly recommended by dermatologists and skin specialist.


Other Skin Whitening Products And Their Effects

Nowadays, the demand for skin whiteners is going up globally. There are plenty of skin lightening treatments, creams, and lotions available over the counter. As with any new product, be sure to read the label and know the facts before you buy and apply.


Bleaching Skin with Skin Lightening Creams and Whitening Lotions

Bleaching skin creams, though popular for decades can be bad for your skin and general well being as it comes with a host of dangers, including irritation, damage or discoloration of the skin, chemical burns, mercury poisoning, and can be able to actually speed up the process of aging.

Chemical hydroquinone which is the most commonly used ingredient in skin whitening products to treat different forms of hyperpigmentation has been reported to have caused serious and severe skin problems and disorders and may actually even worsen hyperpigmentation for darker skin. Products with high levels of this substance are thus unsafe to use and have been prohibited in many countries 4.

Some bleaching skin products made overseas and are being sold online contain harmful chemical mercury as an active ingredient to traditional skin lightening treatments. Exposure to high levels of mercury can cause neurological and kidney impairment.      


  • Microdermabrasion and Dermabrasion

This procedure uses exfoliating crystals to remove dull skin, brown spots, and age spots. It is generally safe for people with fair skin but can result in scarring and hyperpigmentation for people with darker skin. In addition, it also is associated with pain and can cause a lot of discoloration or even irritate the skin.

  • Glutathione Pills

While glutathione is also found in food, dietary consumption doesn’t appear to relate to blood levels. Like many other antioxidants, glutathione is also available in pills. Glutathione Pills are also used as a skin lightening by those who cannot tolerate glutathione injections. However, little did they know that Glutathione pills can raise intracellular glutathione levels with only 5%. research shows taking glutathione itself orally does not boost cellular glutathione levels since it breaks down in the digestive tract before it reaches the cells. Therefore it is of little to no use, unless it can penetrate the cell walls


  • Kojic Acid

It is most often used as a skin lightening agent added to soaps, creams, body lotions, and other cosmetic products because it can inhibit melanin production. However, kojic acid has a relatively poor absorption rate and long-term use may make your skin more susceptible to sunburn and hyperpigmentation. You can use kojic acid to treat areas of hyperpigmentation or scarring, but you shouldn’t use it in an attempt to lighten your natural complexion especially in sensitive areas because it can cause irritation.

skin whitening

Glutathione: Why is it the best skin lightening and how to increase its level?


With the rapid innovation, most of over the counter skin lightening creams already come with vitamin C to give you smoother and whiter skin you desire. While these skin lightening treatments work to a certain level, it is certainly not the best and effective as well or long-lasting treatment just like many other individuals may think. If you opt for safe and effective skin whitening treatment, the use of glutathione injections or suppositories under medical supervision are more efficacious than creams and pills due to following reasons:


  • Glutathione Injections

Glutathione injections produce faster results as compared to all other forms of skin whitening treatments that include creams, pills and use of skin whitening home remedies because they are given directly into the bloodstream and thus get to work immediately bringing changes from within the body. The only truly effective form to increase active glutathione levels in the body is with glutathione injections.


  • Glutathione Suppositories

Glutathione suppositories are one of the most effective ways for the body to fully absorb glutathione without digestive interaction. They are more effective than pills because they are concentrated with a medical strength level that delivers 1000mg of glutathione directly into the bloodstream. Glutathione suppository as the name imply is inserted rectally and then it is dissolved and absorbed into the bloodstream. It is fast acting and fast absorbing. When used regularly, the suppositories also boost the speed of cell turnover and help the body to repair damaged cells faster. Four to six months of constant use is recommended for optimal skin lightening results.

A 500mg of Vitamin C can also be added to glutathione suppositories to help whiten the skin by inhibiting melanogenesis triggered by UV radiation. Vitamin C also triggers a strong reparative effect in the skin by increasing and improving the collagen molecules in order to reverse the UV induced skin damage. Vitamin C, when combined with glutathione, can form into a strong antioxidant that repairs the skin and inhibits skin darkening, thereby making the skin more hydrated, lighter, and radiant.

If glutathione injections are not what you are looking for because of the cost, along with the discomfort of having an injection, then don’t miss out the glutathione suppositories that also offer an amazing effect which you can benefit at the comfort of your home. Plus, it is cost-effective compared to glutathione injections.


Other Health Benefits of Glutathione

  • Can reduce respiratory disease symptoms
  • May reduce the damage of oxidative stress in people with uncontrolled diabetes.
  • Helps the body fight against autoimmune diseases like rheumatoid arthritis, celiac disease, and lupus.
  • Can prevent fatty liver disease.
  • Possibility to  prevent cancer progression
  • Reduction of  symptoms of Parkinson’s disease


What can you do to see the whitening results a lot faster?

In the review published in April 1994 by The Journal of Biological Chemistry, the interaction between Glutathione and vitamin C is described as a partnership which aids in the body’s maintenance of antioxidants. Since glutathione always oxidizes, you need to take another supplement and the best choice is vitamin C. These two help the body getting rid of the harmful effects caused by toxic hydrogen peroxide and free radicals5.

This process happens when the glutathione enables the recycling of dehydroascorbate to Vitamin C. In return, vitamin C performs its role by storing the glutathione in the tissues. However, they have both functions which are independent of one another.

Together, Glutathione and vitamin C are considered to be one of the most effective skin whitening products. They both decrease the production of melanin. As a result, this leads to lighter skin color. Furthermore, vitamin C added to the glutathione creates a longer-lasting effect6.


Is Skin Whitening Safe And Effective?

It is not only safe but it also beneficial to health.

The most crucial fact to remember is that this only works when you are consuming a high-quality product.  In addition, you need to take the appropriate dose to induce a skin whitening effect. That is why at the HCG institute we give you prescription grade safe and effective glutathione treatments.


Why Choose The HCG Institute?

All medications including glutathione injections and suppositories for Skin Whitening from The HCG Institute are manufactured in the USA at partner 503B FDA Registered pharmacies with official regulatory testing to ensure purity and consistency.

Glutathione Injections and suppositories from The HCG Institute can only be administered via medical supervision and a prescription. The HCG Institute serves patient nationwide via telemedicine by our board-certified physicians, thus giving you the best support so you don’t have to leave the comfort of your home.


Medical References:

1. Lu SC. Glutathione synthesis. Biochim Biophys Acta. 2013 May;1830(5):3143-53. doi: 10.1016/j.bbagen.2012.09.008.

2. Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C. Role of glutathione in cancer progression and chemoresistance. Oxid Med Cell Longev. 2013;2013:972913.

3. Watanabe F, Hashizume E, Chan GP, Kamimura A. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women. Clin Cosmet Investig Dermatol. 2014 Oct 17;7:267-74.

4. Desmedt B, Ates G, Courselle P, De Beer JO, Rogiers V, Hendrickx B, Deconinck E, De Paepe K. In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics. Skin Pharmacol Physiol. 2016;29(6):300-308.

5. Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, van Zundert B, Bono MR, Oñate SA, Bustamante M, Cárcamo JG, Rivas CI, Vera JC. Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione. J Biol Chem. 2007 May 25;282(21):15506-15.

6. Lenton KJ, Sané AT, Therriault H, Cantin AM, Payette H, Wagner JR. Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. Am J Clin Nutr. 2003 Jan;77(1):189-95.