Testicular Atrophy Reversal With hCG: Why It Occurs 

Testicular Atrophy is a medical condition in which the testicles, located in the scrotum, shrink in size and may be accompanied by loss of function. This happens most commonly with long term testosterone replacement therapy. When this exogenous testosterone is introduced into the bloodstream and binds to androgen receptors throughout the body, high testosterone levels trick your brain that your testicles are at work. The brain then stops releasing gonadotropin-releasing hormone (GnRH) which stimulates the production of Luteinizing hormone (LH) and Follicle-stimulating hormone (FSH) because the brain assumes that the rise in testosterone levels is a sign that you now have enough testosterone.  FSH and LH cause the testes’ production of testosterone and sperm in the testicle. So while the body enjoys the benefits of high serum testosterone, the testicles begin to shrink because it stops from secreting testosterone.⁴ While this is happening you are thinking about how to prevent testicular shrinkage on testosterone. We can help with hCG therapy.

HCG for Testosterone Replacement Therapy (TRT)

testicular atrophyTestosterone is the main male sex hormone and an anabolic steroid. In male humans, testosterone plays an essential role in the development of male reproductive tissues such as the testes and prostate, as well as promoting secondary sexual characteristics including the growth of facial, body, and pubic hair, increased muscle and bone mass, and deepening of the voice. Moreover, testosterone is also involved in boosting male fertility by improving sperm production. However, the production of testosterone starts to decline as men age.¹ The premature decline in testosterone is also becoming more and more common among younger men, especially in the 20’s and 30’s as a result of their smoking behavior and changes in health status. With this gradual decline, the beneficial effects of testosterone could be diminished and adversely affect physical and emotional well-being. Thus, testosterone replacement therapy (TRT) is commonly used for treatment for men with hypogonadism.

 

Testosterone Replacement Therapy: What is it?

Testosterone replacement therapy (TRT) is a reasonable treatment option for men to improve the signs and symptoms of low testosterone levels. When replaced, many of the positive effects of testosterone are regained.  Doctors may prescribe testosterone as injections, patches, pellets or gels.² Unfortunately, the use of this is not without significant side effects, including testicular atrophy and infertility which can lead to permanent damage when not treated.³

Other Signs And Symptoms of Low T

  1. Erectile dysfunction
  2. Lack of sexual desire
  3. Reduced muscle mass 
  4. Difficulty sleeping
  5. Hair loss
  6. Weight gain
  7. Reduced bone mass

 

How To Prevent Testicular Shrinkage On Testosterone?

how to prevent testicular shrinkage on testosteroneHuman chorionic gonadotropin (HCG) is often associated with women as it is one of the major pregnancy hormones produced by the placenta once implantation occurs. It is also used in conjunction with a low-calorie diet for weight loss. However, hCG can actually be used in men, especially as a part of testosterone replacement therapy to offset the side effects of low T. 

1. Reverses Testicular Atrophy and Shrinkage

HCG  is a glycoprotein hormone that mimics LH (luteinizing hormone) which is also a glycoprotein hormone. Both hormones bind the same transmembrane receptor known as Luteinizing hormone/choriogonadotropin receptor (LHCGR) so it is easy for hCG to grab LH receptors and stimulate them. In men, hCG acts like luteinizing hormone (LH) which stimulates Leydig cells in the testicles resulting in the natural production of testosterone from within the testes. With HCG imitating LH, spermatogenesis acting on Leydig cells located in the testes is regulated by controlling testosterone production. Not only will hCG therapy reverse testicular shrinkage, but it can also help restore your fertility and sperm production by maintaining intra-testicular testosterone levels.

2. Prevents Erectile Dysfunction and Boosts Your Sexual Desire

According to one study, the administration of HCG gave better results in the treatment of erectile failure and lack of sexual desire. 

As men age, testosterone production decreases, leading to erectile dysfunction. Erections are clearly androgen-dependent, so when hCG is administered it will promote hormonal balance, specifically the testosterone level that increases libido.

 

Testicular Atrophy hCG Therapy is Safe and Effective 

HCG for low T is safe when used appropriately with the supervision of your doctor. It shouldn’t be used by men with prostate cancer, certain brain cancers, or uncontrolled thyroid disease. In fact, HCG is approved by the FDA as a treatment for specific conditions in both women and men. Physicians prescribe HCG injections in conjunction with TRT  to combat the symptoms of hypogonadism, such as low T and infertility. Talk with your doctor about your other medical conditions before using hCG. Our healthcare provider will request bloodwork to make sure that you are healthy to do hCG injections.

 

Testicular Atrophy Reversal Therapy With HCG Injections

testicular atrophy reversal therapyMany hCG products are being marketed nowadays claiming incredible results. However, the Food and Drug Administration (FDA) is advising consumers to steer clear of these “homeopathic” human chorionic gonadotropin. There are also no hCG products approved over the counter sales. Homeopathic hCG is one of the most accessible forms but does not contain the powerful hormone so there is no effect at all. Real hCG requires that you obtain a prescription from a doctor who will go over your current health issues. 

At The HCG Institute, we only offer prescription grade hCG along with your testosterone replacement therapy to how to prevent testicular shrinkage on testosterone or restore if you already have testicular atrophy. You will get medical support throughout therapy by doctors, nurses, nurse practitioners, and patient care coordinators who are familiar with hCG therapy for low T. You can start the process by completing the HRT Medical Intake form on our Start Now page, under Step 2.

 

References: 

  1. Martínez Portillo FJ, Cueva Martínez A, Martin Braun P, Fernández Arancibia MI, Jünemann KP, Alken P. [Testosterone substitution in patients with hypogonadism].Arch Esp Urol. 2002 Sep;55(7):827-38. Review. PubMed PMID: 12380312.
  2. Zitzmann M, Nieschlag E. Hormone substitution in male hypogonadism. Mol Cell Endocrinol. 2000 Mar 30;161(1-2):73-88. Review. PubMed PMID: 10773395.
  3. Buvat J, Maggi M, Guay A, Torres LO. Testosterone deficiency in men: systematic review and standard operating procedures for diagnosis and treatment. J Sex Med.2013 Jan;10(1):245-84. doi: 10.1111/j.1743-6109.2012.02783.x. Epub 2012 Sep 12. Review. PubMed PMID: 22971200.
  4. Rosner W. Sex steroids and the free hormone hypothesis. Cell. 2006;124(3):455–456. 
  5. Rabijewski M. [The treatment of hypogonadism and maintenance of fertility in men].Pol Merkur Lekarski. 2016 Mar;40(237):198-201. Review. PubMed PMID: 27088205.