Glutathione Suppositories

Glutathione is a naturally occurring tripeptide made of three amino acids: cysteine, glycine, and glutamic acid. It functions as a water-soluble antioxidant and is involved in Phase II liver metabolic pathways, as documented in the biochemical literature.

The Skin Tone Support formulation adds Vitamin C (ascorbic acid). Vitamin C is a cofactor in a number of enzymatic reactions, including one involved in melanin synthesis regulation, part of why it's sometimes paired with glutathione in formulations intended to support a more even skin tone.

Suppository administration is one route among several used for glutathione supplementation. Research comparing absorption across administration routes (oral, injectable, suppository) is ongoing, and findings vary. The right choice for you is a conversation with your prescribing provider.

Individual results vary significantly and are not guaranteed. Results, if any, are not established on a fixed timeline.

Potential Benefits:

– May support normal antioxidant activity
– May play a role in normal liver metabolic function
– May support normal skin tone as part of a broader skin care approach (Skin Tone Support Regimen)
– May support normal cellular redox balance

These statements describe the physiological roles of glutathione and vitamin C as documented in the scientific literature. They aren't claims that this compounded product diagnoses, treats, cures, or prevents any disease or condition, including cancer or any other serious illness. Any change in skin tone is a gradual process that varies significantly between individuals, isn’t guaranteed, and isn’t established on a fixed timeline.

Product Purchase Includes:

– Medication
– Medical provider consultation
– Program guide

Administration and Frequency:

– Insert suppository rectally
– As directed by your prescribing provider

Contraindications:

Glutathione suppositories may not be appropriate for individuals who:

– Have a known hypersensitivity or allergy to glutathione, Vitamin C, or any component of the formulation
– Have asthma or a history of bronchospasm: glutathione has been associated with bronchoconstriction in some patients, and your provider should evaluate this risk before starting
– Have G6PD deficiency: high-dose Vitamin C has been associated with hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency (Skin Tone Support formulation)
– Have a history of kidney stones or impaired renal function: high-dose Vitamin C may increase oxalate-related risk (Skin Tone Support formulation)
– Have active rectal irritation, fissures, or hemorrhoids that may be aggravated by suppository administration
– Are pregnant or breastfeeding: discuss with your independent licensed healthcare provider before use.

Warnings and Precautions:

– Asthma and respiratory considerations. Bronchospasm has been reported in association with glutathione in patients with asthma or reactive airway disease. Discuss this specifically with your provider before starting.
– G6PD and Vitamin C. Patients with known or suspected G6PD deficiency should discuss the Vitamin C component with their provider before starting the Skin Tone Support formulation.
– Kidney health. Patients with a history of kidney stones or impaired renal function should discuss the Vitamin C component with their provider.
– Local irritation. Suppository administration can cause rectal irritation or discomfort in some patients. Discontinue and contact your provider if irritation is persistent or severe.
– Drug interactions. Glutathione may interact with certain chemotherapy agents and other medications. Disclose all current medication, supplements, and medical conditions to your prescribing provider before starting.

Patients should inform their healthcare provider of all medical conditions, medications, and supplements before receiving this compounded formulation.

Potential Side Effects:

Reported side effects may include:

– Rectal irritation or discomfort
– Nausea
– Headache
– Bronchospasm in patients with asthma; see Warnings above
– Allergic reaction

Seek immediate medical attention for signs of a severe allergic reaction: hives, swelling of the face or throat, wheezing, or difficulty breathing. Contact your prescribing provider promptly for any unexpected or concerning symptoms.