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                    Product Description
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                    Reviews (8)
Semaglutide
Compounded Semaglutide is a once-weekly injection, personalized with either B6, Glycine, or B12, depending on the patient's needs. This compounded medication may help support weight management goals when used as part of a comprehensive program under medical provider supervision. It is specifically formulated for patients who do not tolerate the standard formulation or for those who need a customized treatment approach. All medications come from licensed USA partner pharmacies and are compounded in compliance with section 503A of the Federal Food, Drug, and Cosmetic Act. They are dispensed by our partner pharmacies solely pursuant to a valid patient-specific prescription from a licensed healthcare provider. This is a compounded medication that is not FDA-approved
The addition of B6, B12, or Glycine may be compounded at the discretion of the prescribing healthcare provider based on individual patient needs. The safety and efficacy of these combinations have not been established by the FDA., They are compounded exclusively to meet the clinical needs of patients when commercially available alternatives are not appropriate for the individual.  
If Prescribed, Product Purchase Includes:
– Medication 
– Physician Consultation 
– Syringes
– Alcohol Pads
– Program guide 
– Online and phone support
Administration and Frequency
- Subcutaneous (SQ) Injection
- Once weekly Injection 
- A Step-Up Dosing Schedule is followed
Dosing schedules are determined by your healthcare provider based on individual response and tolerance. The schedules shown are examples only and may differ from your prescribed regimen.
Standard Semaglutide - Step-Up Dosing Schedule:
Weeks 1-4: inject 0.25mg once a week
Weeks 5-8: inject 0.5mg once a week
Weeks 9-12: inject 1mg once a week
Weeks 13-16: inject 1.7mg once a week
Weeks 17-20 and after: inject 2.4mg once a week - Maintenance Dose 
Sema Max and Ultra Sema Max 10-Week Programs
Our ten-week Compounded Semaglutide injection program combined with Vitamin B6 or B12, depending on the patient's personalization needs. This program has additional criteria for approval based on a comprehensive medical review and patient qualifications. The accelerated dosing differes from FDA-approved protocols and should be followed only under close medical supervision. It will not be appropriate for all patients.
Semaglutide Max Step-Up Accelerated Dosing Schedule:
Week 1: Inject 0.5mg once a week
Week 2: Inject 1mg once a week
Week 3: Inject 1.5mg once a week
Week 4: Inject 2mg once a week
Week 5-10: Inject 2.4mg once a week - Maintenance Dose 
If you desire further weight loss after the Sema Max program is complete, purchase Step 4 as a maintenance regimen.
Disclaimer: The FDA does not approve nor review compounded products for safety, effectiveness, or quality. Compounded Semaglutide is not the same as Ozempic®, Wegovy®, Zepbound® or Mounjaro®, which are FDA-approved. Compounded versions may not meet the standards that brand names have met. Data from clinical trials for FDA-approved medications should not be utilized to make decisions related to compounded medications.
FDA-approved medications such as Saxenda®, Victoza®, Wegovy®, and Ozempic® are trademarks of Novo Nordisk™, while Mounjaro™ is a product of Eli Lilly and Company™. The HCG Institute is not associated with or endorsed by these companies or their products. We do not supply these medications. If you have questions or concerns about your health or are interested in these products, please consult a healthcare professional.
The HCG Institute is a patient management platform that partners with independent licensed physician networks to deliver medical services through our infrastructure. All medications come from licensed USA partner pharmacies and are compounded in compliance with section 503A of the Federal Food, Drug, and Cosmetic Act. They are dispensed by our partner pharmacies solely pursuant to a valid patient-specific prescription from a licensed healthcare provider.
Medication will only be prescribed by a licensed clinician if deemed medically appropriate after a thorough consultation. Providers may prescribe compounded medications as needed to meet patient requirements. Results are not guaranteed and may vary based on the individual as part of a personalized weight loss program. This site is an advertisement for telehealth services, and any treatment or prescription is at the sole discretion of the prescribing provider.
Actual medication form and appearance may differ from what is shown. Information on this website is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. If you have health-related questions or concerns, please consult your doctor.
Customer Reviews
- Great Review by RG
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 I lost 30 pounds in 12 weeks. A little nausea at first then it was smooth sailing. (Posted on 5/22/2025)How Many Stars Do You Rate This Item? 
- love it Review by skinny shots
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 I have been using these for the last three months and have lost so much weight. Sema really works! (Posted on 9/17/2024)How Many Stars Do You Rate This Item? 
- Semaglutide Injections - Highly recommend Review by Julia A.
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 Sema has been a game-changer for me. My appetite has decreased and after eating a small amount I feel full. As an added and very significant bonus, my craving for wine has almost disappeared. Wine used to be my downfall when trying to lose weight because after a stressful day, I wanted a glass or two of wine to relax. And after a glass or two of wine, I ate more. When I first started sema, I had severe heartburn after eating for the first 2-3 weeks. This subsided once I figured out how much to eat and also to eat earlier in the day. Ever since I have had no issues. I have been on sema for approximately 3 months and have lost 25 pounds without much effort. Losing weight hasn't been a struggle with sema. I'm not hungry, tired, or irritable which was always par for the course for other diets. Highly recommend sema if you can power through the side effects of the first few weeks. (Posted on 2/2/2023)How Many Stars Do You Rate This Item? 
- Semaglutide Injections Review by Molly
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 Love this product, has helped in my weight loss and the B12 is an added bonus (Posted on 12/4/2022)How Many Stars Do You Rate This Item? 
- Semaglutide Injections - Wow! Review by Dana
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 Best, fastest weight loss product ever! (Posted on 11/15/2022)How Many Stars Do You Rate This Item? 
- Semaglutide Injections - I’ve lost nearly all of the weight! Review by April
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 With a low calorie diet and exercise, this boosted my weight loss drastically. I was averaging a loss 1.25 lbs a week on my own. Admittedly, my exercise plan was ambitious and I wasn’t able to maintain it easily. Since starting the injections, I’ve been able to average 3.5 lbs loss per week. Lots of exercise is key, but I’ve had weeks where I couldn’t exercise more than a 30 min walk per day and still lost 2lbs.How Many Stars Do You Rate This Item? 
 
 If you follow the meal guidelines and adjust your calories for your goals… Sema definitely helps push things to the next level.
 
 I strongly recommend minding your macros and eating plenty of proteins. I had some muscle loss in the beginning but adjusted my diet to help with that. (Posted on 9/28/2022)
- Semaglutide Injections - Great Product! Review by Meredith
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 This product has worked really well for me and in a month I’m down 7lbs. Looking forward to seeing more results! (Posted on 9/9/2022)How Many Stars Do You Rate This Item? 
- Semaglutide Injections - Muy buena Review by Cocuya
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 Me encantó este producto!!!! (Posted on 3/16/2022)How Many Stars Do You Rate This Item? 
